IUPAC-NIST Solubilities Database

IUPAC-NIST Solubility Database
NIST Standard Reference Database 106

Solubility System: 2-Propanol with Cyclohexane and Water

Components:
   (1) Water; H2O; [7732-18-5]  NIST Chemistry WebBook for detail
   (2) 2-Propanol (isopropanol, isopropyl alcohol); C3H8O; [67-63-0]  NIST Chemistry WebBook for detail
   (3) Cyclohexane; C6H12; [110-82-7]  NIST Chemistry WebBook for detail

Original Measurements:
   Plackov, D.; Stern, I., Fluid. Phase Equilib. 71, 189 (1992).

Variables:
   Temperature = 298 K

Prepared By:
   A. Skrzecz

Experimental Data:   (Notes on the Nomenclature)

Compositions along the saturation curve
t/°C	T/K	Mass Fraction w₁ (compiler)	Mass Fraction w₂ (compiler)	Mole Fraction x₁	Mole Fraction x₂
25	298.2	0.0273	0.9722	0.0378	0.9601
25	298.2	0.0770	0.9191	0.1031	0.8793
25	298.2	0.1031	0.8910	0.1359	0.8384
25	298.2	0.1568	0.8308	0.1982	0.7497
25	298.2	0.2104	0.7683	0.2534	0.6608
25	298.2	0.2766	0.6861	0.3105	0.5500
25	298.2	0.3596	0.5742	0.3632	0.4141
25	298.2	0.4141	0.4922	0.3841	0.3260
25	298.2	0.4794	0.3842	0.3966	0.2270
25	298.2	0.5165	0.3081	0.3909	0.1665
25	298.2	0.5443	0.2333	0.3747	0.1147
25	298.2	0.5522	0.1866	0.3547	0.0856
25	298.2	0.5405	0.1104	0.3030	0.0442
25	298.2	0.4708	0.0575	0.2258	0.0197
25	298.2	0.4269	0.0258	0.1880	0.0081
25	298.2	0.3883	0.0144	0.1624	0.0043
25	298.2	0.3330	0.0092	0.1314	0.0026
25	298.2	0.2658	0.0023	0.0981	0.0006
25	298.2	0.2222	0.0016	0.0790	0.0004
25	298.2	0.1513	0.0013	0.0508	0.0003
25	298.2	0.0698	0.0009	0.0220	0.0002

Compositions of coexisting phases
t/°C	T/K	Mass Fraction w₁ (compiler)	Mass Fraction w₂ (compiler)	Mole Fraction x₁	Mole Fraction x₂	Comment(s)
25	298.2	0.014	0.985	0.020	0.977	hydrocarbon-rich phase
25	298.2	0.057	0.940	0.077	0.908	hydrocarbon-rich phase
25	298.2	0.114	0.875	0.147	0.807	hydrocarbon-rich phase
25	298.2	0.149	0.838	0.188	0.755	hydrocarbon-rich phase
25	298.2	0.177	0.805	0.218	0.708	hydrocarbon-rich phase
25	298.2	0.229	0.744	0.269	0.624	hydrocarbon-rich phase
25	298.2	0.292	0.669	0.325	0.531	hydrocarbon-rich phase
25	298.2	0.152	0.000	0.051	0.000	water-rich phase
25	298.2	0.260	0.008	0.096	0.002	water-rich phase
25	298.2	0.359	0.014	0.146	0.004	water-rich phase
25	298.2	0.422	0.022	0.184	0.007	water-rich phase
25	298.2	0.449	0.028	0.203	0.009	water-rich phase
25	298.2	0.508	0.066	0.257	0.024	water-rich phase
25	298.2	0.553	0.102	0.311	0.041	water-rich phase

Method/Apparatus/Procedure:
   Binodal compositions were determined by titration with the corresponding, less-soluble component until the appearance of turbidity. The analytical method was used for determination of tie-lines. This was based on refractive indexes and densities of the samples, combined with the oxidation of the alcohol with an excess of potassium dichromate and determination of unreduced dichromate with Na₂S₂O₃. Alcohol in the organic layer was determined after extraction with water.

Source and Purity of Materials:
   (1) Kemika (Zagreb); analytical grade; presumably used as received; n=1.3475, p(25°C)=780.8 kg/m³, b.p.=81.1°C.
   (2) Merck Alkaloid; purity not specified; presumably used as received; n=1.4232, p(25°C)=773.4 kg/m³, b.p.=80.1°C.
   (3) Twice distilled in the presence of KMnO₄

Estimated Errors:
   Solubility: Not reported.
   Temperature: Composition <0.0005 mass fraction, binodal, (relative); composition ±2%, tie line.

References:
   ¹ D. Plackov, and I. Stern, Fluid Phase Equilib. 57, 327 (1990).