IUPAC-NIST Solubility Database
NIST Standard Reference Database 106

Glass Ball as Bullet Solubility System: Acetonitrile with 12-Tricosanone
Components:
   (1) 12-Tricosanone; C23H46O; [540-09-0]  NIST Chemistry WebBook for detail
   (2) Acetonitrile; C2H3N; [75-05-8]  NIST Chemistry WebBook for detail
Original Measurements:
   Garland , F.M.; Hoerr, C.W.; Pool, W.O.; Ralston, A.W., J. Org. Chem. 8, 344-57 (1943).

 Variables:
   Temperature = 283 Kto 355 K

 Prepared By:
   Valerii P. Sazonov

 Experimental Remarks:
   The solubilities of 12-tricosanone (2) in acetonitrile (1) in mass percent including the region of immisciblity over the indicated temperature range were reported in graphical form and in a table. Monotectic equilibrium is realized at 62.3 °C (335.5 K, compiler). The upper critical solution temperature was reported to be above 82 °C.

 Experimental Data:   (Notes on the Nomenclature)
  
Solubility of 12-tricosanone (2) in acetonitrile (1)
t/°CT/Kg2/100 g solution102 * Mass Fraction w2 (compiler)Mole Fraction x2 (compiler)
10.0283.2<0.1<0.1 (a)0.0001
23.3 (c)296.5-0.3 (a)0.0004
30.0303.20.40.4 (a)0.0005
35.0 (c)308.2-0.5 (a)0.0006
45.9 (c)319.1-0.7 (a)0.0009
50.0323.21.21.2 (a)0.0015
53.0 (c)326.2-1.9 (a)0.002
56.1 (c)329.3-3.1 (a)0.004
60.4 (c)333.6-6.2 (a)0.008
62.7 (c)335.9-82.3 (a)0.361
63.4 (c)336.6-87.8 (a)0.466
64.5 (c)337.7-91.8 (a)0.576
65.5 (c)338.7-9.3 (b)0.012
65.9 (c)339.1-95.0 (a)0.697
66.4 (c)339.6-79.5 (b)0.320
70.0343.212.411.0 (b)0.015
72.7 (c)345.9-78.0 (b)0.301
74.8 (c)348.0-13.2 (b)0.018
75.1 (c)348.3-77.1 (b)0.290
80.5 (c)353.7-16.2 (b)0.023
81.1 (c)354.3-74.3 (b)0.260
82.0355.222.818.6 (b)0.027
 Notes:
   a  Solid-liquid equilibrium.
   b  Liquid-liquid equilibrium.
   c  The compiler extracted these data from the published graphs.

 Method/Apparatus/Procedure:
   The synthetic method was used. The solubilities of (2) in (1) were determined in sealed tubes by the method and apparatus described elsewhere.1,2

 Source and Purity of Materials:
   (1) Source not specified; best grade reagent; dried and twice distilled.
   (2) Obtained from the ketoesters by hydrolyzing with 5 % alcoholic potassium hydroxide; purified by several recrystallizations from ethanol; freezing point = 69.3 °C.

 Estimated Errors:

   Temperature: ± 0.2 K.

 References:
   1. A. W. Ralston, C. W. Hoerr, and E. J. Hoffman, J. Am. Chem. Soc. 64, 1516 (1942).
   2. C. W. Hoerr and A. W. Ralston, J. Am. Chem. Soc. 64, 2824 (1942).