IUPAC-NIST Solubility Database
NIST Standard Reference Database 106

Glass Ball as Bullet Solubility System: Acetonitrile with 12-Tricosanone

   (1) 12-Tricosanone; C23H46O; [540-09-0]  NIST Chemistry WebBook for detail
   (2) Acetonitrile; C2H3N; [75-05-8]  NIST Chemistry WebBook for detail

Original Measurements:
   Garland , F.M.; Hoerr, C.W.; Pool, W.O.; Ralston, A.W., J. Org. Chem. 8, 344-57 (1943).

   Temperature = 283 Kto 355 K

Prepared By:
   Valerii P. Sazonov

Experimental Remarks:

   The solubilities of 12-tricosanone (2) in acetonitrile (1) in mass percent including the region of immisciblity over the indicated temperature range were reported in graphical form and in a table. Monotectic equilibrium is realized at 62.3 °C (335.5 K, compiler). The upper critical solution temperature was reported to be above 82 °C.

Experimental Data:   (Notes on the Nomenclature)
Solubility of 12-tricosanone (2) in acetonitrile (1)
t/°CT/Kg2/100 g solution102 * Mass Fraction w2 (compiler)Mole Fraction x2 (compiler)
10.0283.2<0.1<0.1 (a)0.0001
23.3 (c)296.5-0.3 (a)0.0004
30.0303.20.40.4 (a)0.0005
35.0 (c)308.2-0.5 (a)0.0006
45.9 (c)319.1-0.7 (a)0.0009
50.0323.21.21.2 (a)0.0015
53.0 (c)326.2-1.9 (a)0.002
56.1 (c)329.3-3.1 (a)0.004
60.4 (c)333.6-6.2 (a)0.008
62.7 (c)335.9-82.3 (a)0.361
63.4 (c)336.6-87.8 (a)0.466
64.5 (c)337.7-91.8 (a)0.576
65.5 (c)338.7-9.3 (b)0.012
65.9 (c)339.1-95.0 (a)0.697
66.4 (c)339.6-79.5 (b)0.320
70.0343.212.411.0 (b)0.015
72.7 (c)345.9-78.0 (b)0.301
74.8 (c)348.0-13.2 (b)0.018
75.1 (c)348.3-77.1 (b)0.290
80.5 (c)353.7-16.2 (b)0.023
81.1 (c)354.3-74.3 (b)0.260
82.0355.222.818.6 (b)0.027
   a  Solid-liquid equilibrium.
   b  Liquid-liquid equilibrium.
   c  The compiler extracted these data from the published graphs.

   The synthetic method was used. The solubilities of (2) in (1) were determined in sealed tubes by the method and apparatus described elsewhere.1,2

Source and Purity of Materials:
   (1) Source not specified; best grade reagent; dried and twice distilled.
   (2) Obtained from the ketoesters by hydrolyzing with 5 % alcoholic potassium hydroxide; purified by several recrystallizations from ethanol; freezing point = 69.3 °C.

Estimated Errors:

   Temperature: ± 0.2 K.

   1. A. W. Ralston, C. W. Hoerr, and E. J. Hoffman, J. Am. Chem. Soc. 64, 1516 (1942).
   2. C. W. Hoerr and A. W. Ralston, J. Am. Chem. Soc. 64, 2824 (1942).