IUPAC-NIST Solubility Database
NIST Standard Reference Database 106

Glass Ball as Bullet Solubility System: Acetonitrile with 14-Heptacosanone
Components:
   (1) 14-Heptacosanone; C27H54O; [542-50-7]  NIST Chemistry WebBook for detail
   (2) Acetonitrile; C2H3N; [75-05-8]  NIST Chemistry WebBook for detail
Original Measurements:
   Garland , F.M.; Hoerr, C.W.; Pool, W.O.; Ralston, A.W., J. Org. Chem. 8, 344-57 (1943).

 Variables:
   Temperature = 303 K to 355 K

 Prepared By:
   Valerii P. Sazonov

 Experimental Remarks:
   The solubilities of 14-heptacosanone (2) in acetonitrile (1) in mass percent including the region of immisciblity over the indicated temperature range were reported in graphical form and in a table. Monotectic equilibrium is realized at 71.8 °C (345.0 K, compiler). The upper critical solution temperature was reported to be above 82 °C.

 Experimental Data:   (Notes on the Nomenclature)
  
Solubility of 14-heptacosanone (2) in acetonitrile (1)
t/°CT/Kg2/100 g solution102 * Mass Fraction w2 (compiler)Mole Fraction x2 (compiler)
30.0303.2≈ 0.1≈ 0.1 (a)0.0001
50.0323.20.20.2 (a)0.0002
55.6 (c)328.8-0.3 (a)0.0003
62.1 (c)335.3-1.0 (a)0.001
68.2 (c)341.4-2.7 (a)0.003
70.0343.24.13.9 (a)0.004
70.9 (c)344.1-4.5 (a)0.005
72.0 (c)345.2-85.9 (b)0.388
72.2 (c)345.4-88.2 (a)0.437
72.5 (c)345.7-91.8 (a)0.538
74.5 (c)347.7-96.4 (a)0.736
77.3 (c)350.5-6.4 (b)0.007
77.3 (c)350.5-84.8 (b)0.367
82.0355.28.17.5 (b)0.008
82.0 (c)355.2-83.6 (b)0.347
 Notes:
   a  Solid-liquid equilibrium.
   b  Liquid-liquid equilibrium.
   c  Data extracted from the published graphs by the compiler.

 Method/Apparatus/Procedure:
   The synthetic method was used. The solubilities of (2) in (1) were determined in sealed tubes by the method and apparatus described elsewhere.1,2

 Source and Purity of Materials:
   (1) Source not specified; best grade reagent; dried and twice distilled.
   (2) Obtained from the ketoesters by hydrolyzing with 5 % alcoholic potassium hydroxide; purified by several crystallizations from ethanol; freezing point = 77.2 °C.

 Estimated Errors:

   Temperature: ± 0.2 K.

 References:
   1. A. W. Ralston, C. W. Hoerr, and E. J. Hoffman, J. Am. Chem. Soc. 64, 1516 (1942).
   2. C. W. Hoerr and A. W. Ralston, J. Am. Chem. Soc. 64, 2824 (1942).