IUPAC-NIST Solubility Database
NIST Standard Reference Database 106

Glass Ball as Bullet Solubility System: Acetonitrile with 14-Heptacosanone

   (1) 14-Heptacosanone; C27H54O; [542-50-7]  NIST Chemistry WebBook for detail
   (2) Acetonitrile; C2H3N; [75-05-8]  NIST Chemistry WebBook for detail

Original Measurements:
   Garland , F.M.; Hoerr, C.W.; Pool, W.O.; Ralston, A.W., J. Org. Chem. 8, 344-57 (1943).

   Temperature = 303 K to 355 K

Prepared By:
   Valerii P. Sazonov

Experimental Remarks:

   The solubilities of 14-heptacosanone (2) in acetonitrile (1) in mass percent including the region of immisciblity over the indicated temperature range were reported in graphical form and in a table. Monotectic equilibrium is realized at 71.8 °C (345.0 K, compiler). The upper critical solution temperature was reported to be above 82 °C.

Experimental Data:   (Notes on the Nomenclature)
Solubility of 14-heptacosanone (2) in acetonitrile (1)
t/°CT/Kg2/100 g solution102 * Mass Fraction w2 (compiler)Mole Fraction x2 (compiler)
30.0303.2≈ 0.1≈ 0.1 (a)0.0001
50.0323.20.20.2 (a)0.0002
55.6 (c)328.8-0.3 (a)0.0003
62.1 (c)335.3-1.0 (a)0.001
68.2 (c)341.4-2.7 (a)0.003
70.0343.24.13.9 (a)0.004
70.9 (c)344.1-4.5 (a)0.005
72.0 (c)345.2-85.9 (b)0.388
72.2 (c)345.4-88.2 (a)0.437
72.5 (c)345.7-91.8 (a)0.538
74.5 (c)347.7-96.4 (a)0.736
77.3 (c)350.5-6.4 (b)0.007
77.3 (c)350.5-84.8 (b)0.367
82.0355.28.17.5 (b)0.008
82.0 (c)355.2-83.6 (b)0.347
   a  Solid-liquid equilibrium.
   b  Liquid-liquid equilibrium.
   c  Data extracted from the published graphs by the compiler.

   The synthetic method was used. The solubilities of (2) in (1) were determined in sealed tubes by the method and apparatus described elsewhere.1,2

Source and Purity of Materials:
   (1) Source not specified; best grade reagent; dried and twice distilled.
   (2) Obtained from the ketoesters by hydrolyzing with 5 % alcoholic potassium hydroxide; purified by several crystallizations from ethanol; freezing point = 77.2 °C.

Estimated Errors:

   Temperature: ± 0.2 K.

   1. A. W. Ralston, C. W. Hoerr, and E. J. Hoffman, J. Am. Chem. Soc. 64, 1516 (1942).
   2. C. W. Hoerr and A. W. Ralston, J. Am. Chem. Soc. 64, 2824 (1942).