IUPAC-NIST Solubility Database
NIST Standard Reference Database 106

Glass Ball as Bullet Solubility System: Acetonitrile with 16-Hentricontanone

   (1) 16-Hentricontanone; C31H62O; [502-73-8]  NIST Chemistry WebBook for detail
   (2) Acetonitrile; C2H3N; [75-05-8]  NIST Chemistry WebBook for detail

Original Measurements:
   Garland , F.M.; Hoerr, C.W.; Pool, W.O.; Ralston, A.W., J. Org. Chem. 8, 344-57 (1943).

   Temperature = 323 K to 355 K

Prepared By:
   Valerii P. Sazonov

Experimental Remarks:

   The solubilities of 16-hentricontanone (2) in acetonitrile (1) in mass percent including the region of immisciblity over the indicated temperature range were reported in graphical form and in a table. Monotectic equilibrium is realized at 78.2 °C (351.4 K, compiler). The upper critical solution temperature was reported to be above 82 °C.

Experimental Data:   (Notes on the Nomenclature)
Solubility of 16-hentricontanone (2) in acetonitrile (1)
t/°CT/Kg2/100 g solution102 * Mass Fraction w2 (compiler)Mole Fraction x2 (compiler)
50.0323.2≈ 0.1≈ 0.1 (a)0.0001
61.4 (c)334.6-0.2 (a)0.0002
67.8 (c)341.0-0.9 (a)0.0008
70.0343.21.01.0 (a)0.0009
76.4 (c)349.6-2.3 (a)0.002
78.5 (c)351.7-90.0 (a)0.450
79.1 (c)352.3-91.6 (a)0.498
80.5 (c)353.7-95.5 (a)0.659
81.4 (c)354.6-96.6 (a)0.721
82.0355.23.33.2 (b)0.003
   a  Solid-liquid equilibrium.
   b  Liquid-liquid equilibrium.
   c  These data were extracted by the compiler from the published graphs.

   The synthetic method was used. The solubilities of (2) in (1) were determined in sealed tubes by the method and apparatus described elsewhere.1,2

Source and Purity of Materials:
   (1) Source not specified; best grade reagent; dried and twice distilled.
   (2) Obtained from the ketoesters by hydrolyzing with 5 % alcoholic potassium hydroxide; purified by several crystallizations from ethanol; freezing point = 83.7 °C.

Estimated Errors:

   Temperature: ± 0.2 K.

   1. A. W. Ralston, C. W. Hoerr, and E. J. Hoffman, J. Am. Chem. Soc. 64, 1516 (1942).
   2. C. W. Hoerr and A. W. Ralston, J. Am. Chem. Soc. 64, 2824 (1942).