IUPAC-NIST Solubility Database
NIST Standard Reference Database 106

Glass Ball as Bullet Solubility System: Acetonitrile with 16-Hentricontanone
Components:
   (1) 16-Hentricontanone; C31H62O; [502-73-8]  NIST Chemistry WebBook for detail
   (2) Acetonitrile; C2H3N; [75-05-8]  NIST Chemistry WebBook for detail
Original Measurements:
   Garland , F.M.; Hoerr, C.W.; Pool, W.O.; Ralston, A.W., J. Org. Chem. 8, 344-57 (1943).

 Variables:
   Temperature = 323 K to 355 K

 Prepared By:
   Valerii P. Sazonov

 Experimental Remarks:
   The solubilities of 16-hentricontanone (2) in acetonitrile (1) in mass percent including the region of immisciblity over the indicated temperature range were reported in graphical form and in a table. Monotectic equilibrium is realized at 78.2 °C (351.4 K, compiler). The upper critical solution temperature was reported to be above 82 °C.

 Experimental Data:   (Notes on the Nomenclature)
  
Solubility of 16-hentricontanone (2) in acetonitrile (1)
t/°CT/Kg2/100 g solution102 * Mass Fraction w2 (compiler)Mole Fraction x2 (compiler)
50.0323.2≈ 0.1≈ 0.1 (a)0.0001
61.4 (c)334.6-0.2 (a)0.0002
67.8 (c)341.0-0.9 (a)0.0008
70.0343.21.01.0 (a)0.0009
76.4 (c)349.6-2.3 (a)0.002
78.5 (c)351.7-90.0 (a)0.450
79.1 (c)352.3-91.6 (a)0.498
80.5 (c)353.7-95.5 (a)0.659
81.4 (c)354.6-96.6 (a)0.721
82.0355.23.33.2 (b)0.003
 Notes:
   a  Solid-liquid equilibrium.
   b  Liquid-liquid equilibrium.
   c  These data were extracted by the compiler from the published graphs.

 Method/Apparatus/Procedure:
   The synthetic method was used. The solubilities of (2) in (1) were determined in sealed tubes by the method and apparatus described elsewhere.1,2

 Source and Purity of Materials:
   (1) Source not specified; best grade reagent; dried and twice distilled.
   (2) Obtained from the ketoesters by hydrolyzing with 5 % alcoholic potassium hydroxide; purified by several crystallizations from ethanol; freezing point = 83.7 °C.

 Estimated Errors:

   Temperature: ± 0.2 K.

 References:
   1. A. W. Ralston, C. W. Hoerr, and E. J. Hoffman, J. Am. Chem. Soc. 64, 1516 (1942).
   2. C. W. Hoerr and A. W. Ralston, J. Am. Chem. Soc. 64, 2824 (1942).