IUPAC-NIST Solubilities Database

IUPAC-NIST Solubility Database
NIST Standard Reference Database 106

Solubility System: Acetonitrile with Octanamide

Components:
   (1) Acetonitrile; C2H3N; [75-05-8]  NIST Chemistry WebBook for detail
   (2) Octanamide; C8H17NO; [629-01-6]  NIST Chemistry WebBook for detail

Original Measurements:
   Ralston, A.W.; Hoerr, C.W.; Pool, W.O., J. Org. Chem. 8, 473-88 (1943).

Variables:
   Temperature = 283 K to 355 K

Prepared By:
   Valerii P. Sazonov and Nikolai V. Sazonov

Experimental Remarks:

   The solubilities of octanamide (2) in acetonitrile (1) in mass percent over the indicated temperature range were reported in graphical form and in a table.

Experimental Data:   (Notes on the Nomenclature)

Solubility of octanamide (2) in acetonitrile (1)
t/°C	T/K	g₂/100 g solution	10² * Mass Fraction w₂ (compiler)	Mole Fraction x₂ (compiler)
10.0	283.2	1.1	1.1	0.003
21.8*	295.0	-	2.8	0.008
30.0	303.2	5.4	5.1	0.015
40.5*	313.7	-	8.7	0.027
50.0	323.2	16.4	14.1	0.045
58.2*	331.4	-	20.9	0.070
60.0	333.2	31.6	24.0	0.083
69.1*	342.3	-	39.5	0.158
70.0	343.2	73.0	42.2	0.173
78.2*	351.4	-	58.7	0.289
82.0	355.2	200	66.7	0.365

Notes:
   ^*  The compiler extracted these data from the published graphs.

Method/Apparatus/Procedure:
   The synthetic method was used. The solubilities of (2) in (1) were determined in sealed tubes by the method and apparatus described elsewhere.^1,2

Source and Purity of Materials:
   (1) Source not specified; best grade reagent; dried and twice distilled.
   (2) Prepared by passing of ammonia through octanoic acid at 190 °C to 210 °C for 10 hours to 14 hours; purified by recrystallization; freezing point = 105.9 °C.

Estimated Errors:

   Temperature: ± 0.2 K.

References:
   1. A. W. Ralston, C. W. Hoerr, and E. J. Hoffman, J. Am. Chem. Soc. 64, 1516 (1942).
   2. C. W. Hoerr and A. W. Ralston, J. Am. Chem. Soc. 64, 2824 (1942).