IUPAC-NIST Solubilities Database

IUPAC-NIST Solubility Database
NIST Standard Reference Database 106

Solubility System: Acetonitrile with Dodecanamide

Components:
   (1) Dodecanamide; C12H25NO; [1120-162-7]  NIST Chemistry WebBook for detail
   (2) Acetonitrile; C2H3N; [75-05-8]  NIST Chemistry WebBook for detail

Original Measurements:
   Ralston, A.W.; Hoerr, C.W.; Pool, W.O., J. Org. Chem. 8, 473-88 (1943).

Variables:
   Temperature = 283 K to 355 K

Prepared By:
   Valerii P. Sazonov and Nikolai V. Sazonov

Experimental Remarks:

   The solubilities of decanamide (2) in acetonitrile (1) in mass percent over the indicated temperature range were reported in graphical form and in a table.

Experimental Data:   (Notes on the Nomenclature)

Solubility of dodecanamide(2) in acetonitrile (1)
t/°C	T/K	g₂/100 g solution	10² * Mass Fraction w₂ (compiler)	Mole Fraction x₂ (compiler)
10.0	283.2	0.3	0.3	0.0006
30.0	303.2	0.9	0.9	0.002
32.5*	305.7	-	1.1	0.002
45.6*	318.8	-	3.5	0.007
50.0	323.2	5.1	4.9	0.010
51.5*	324.7	-	5.2	0.011
56.6*	329.8	-	8.0	0.018
60.0	333.2	12.1	10.8	0.024
66.0*	339.2	-	18.4	0.044
70.0	343.2	39.8	28.5	0.076
73.5*	346.7	-	37.3	0.109
77.7*	350.9	-	51.2	0.178
81.1*	354.3	-	61.4	0.247
82.0	355.2	175	63.6	0.265

Notes:
   ^*  Data extracted from the published graphs by the compiler.

Method/Apparatus/Procedure:
   The synthetic method was used. The solubilities of (2) in (1) were determined in sealed tubes by the method and apparatus described elsewhere.^1,2

Source and Purity of Materials:
   (1) Source not specified; best grade reagent; dried and twice distilled.
   (2) Prepared by passing of ammonia through dodecanoic acid at 190 °C to 210 °C for 10 hours to 14 hours; purified by recrystallization; freezing point = 102.4 °C.

Estimated Errors:

   Temperature: ± 0.2 K.

References:
   1. A. W. Ralston, C. W. Hoerr, and E. J. Hoffman, J. Am. Chem. Soc. 64, 1516 (1942).
   2. C. W. Hoerr and A. W. Ralston, J. Am. Chem. Soc. 64, 2824 (1942).