IUPAC-NIST Solubilities Database

IUPAC-NIST Solubility Database
NIST Standard Reference Database 106

Solubility System: Biphenyl with Cyclohexane

Components:
   (1) Cyclohexane; C6H12; [110-82-7]  NIST Chemistry WebBook for detail
   (2) Biphenyl; C12H10; [92-52-4]  NIST Chemistry WebBook for detail

Evaluator:
   W.E. Acree, Jr. Department of Chemistry University of North Texas Denton, Texas 76203-5068 (USA) June, 1994.

Critical Evaluation:

   Biphenyl solubilities in cyclohexane were retrieved from papers by Choi et al. (1), McLaughlin and Zainal (2), Acree et al. (3), Acree (4) and Chang (5). The first two studies report observed values at several temperatures, Acree et al. determined values at 303, 308 and 313 K, and the latter two studies give the mole fraction solubility at 298 K. There is not a prior reason to exclude any of the five studies from the critical evaluation.
Regressional analysis of the experimental data as Ln x₁ versus 1/T yielded the following mathematical relationship:
Ln x₁ = - 4295.7 (1/T) + 12.770 (r = 0.9975)
for variation of biphenyl solubility with absolute temperature (see graph below). Back-calculated solubility at 298 K is x₁ = 0.1944, and differs by about 1 - 2 % from experimental values of x₁ = 0.1921 (4) and x₁ = 0.190 (5).

Experimental Data:   (Notes on the Nomenclature)

View Figure 1 for this Evaluation

References: (Click a link to see its experimental data associated with the reference)

   1  Choi, P.B.; Williams, C.P.; Buehring, K.G.; McLaughlin, E., J. Chem. Eng. Data 1985, 30, 403-409.
   2  McLaughlin, E.; Zainal, H.A., J. Chem. Soc. 1960, 3854-3857.
   3  Acree, W.E., Jr.; Pontikos, N.M.; Judy, C.L., Int. J. Pharm. 1986, 31, 225-230.
   4  Acree, W.E., Jr., Int. J. Pharm. 1984, 18, 47-52.
   5  Chang, W., Ph.D Dissertation, North Dakota State University, North Dakota, USA (1969).